Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869369 | 0.85 | HTT (0.51) | ALDH1A1TSHRLMNAMAOBCYP3A4 | |
| SCHEMBL9731847 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAMAOBPYCR1 | |
| SCHEMBL18342570 | 0.78 | HDAC3 (0.45) | ALDH1A1TSHRLMNAMAOBCNR2 | |
| SCHEMBL2584302 | 0.78 | PYCR1 (0.66) | ALDH1A1TSHRLMNAMAOBPYCR1 | |
| SCHEMBL1174217 | 0.77 | MAOB (0.64) | ALDH1A1TSHRLMNAMAOBPYCR1 | |
| SCHEMBL134524 | 0.77 | TSHR (0.60) | ALDH1A1TSHRCNR2CA2AOC3 | |
| SCHEMBL6545115 | 0.77 | TSHR (0.57) | ALDH1A1TSHRLMNACNR2BLM | |
| SCHEMBL12049793 | 0.75 | CNR2 (0.64) | ALDH1A1TSHRCNR2CA2AOC3 | |
| Ammonia Solution, Strong SCHEMBL1348044 | 0.75 | CNR2 (0.58) | ALDH1A1TSHRCNR2CA2AOC3 | |
| Bromide SCHEMBL6760453 | 0.75 | CNR2 (0.58) | ALDH1A1TSHRCNR2CA2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564972-B1 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AG (DE) | 1999-08-11 | — | — | EP | claimed |
| US-5597803-A | POLYPEPTIDES FOR ANTIINFLAMMATORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-28 | — | — | US | claimed |
| EP-0564972-B1 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AG (DE) | 1999-08-11 | — | — | EP | disclosed |