Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505386 | 1.00 | TP53 (0.50) | TP53NOTUMALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL2951054 | 0.91 | NOTUM (0.58) | TP53NOTUMALDH1A1MAPTLMNA | |
| SCHEMBL8925548 | 0.82 | MAPT (0.50) | ALDH1A1ALDH3A1ALDH1A3MAPTLMNA | |
| SCHEMBL8925543 | 0.82 | MAPT (0.50) | ALDH1A1ALDH3A1ALDH1A3MAPTLMNA | |
| SCHEMBL28209311 | 0.79 | TP53 (0.46) | TP53NOTUMALDH1A1MAPTLMNA | |
| SCHEMBL21594514 | 0.78 | ALDH1A1 (0.63) | ALDH1A1ALDH3A1ALDH1A3MAPTLMNA | |
| SCHEMBL11571151 | 0.77 | KDM4E (0.64) | ALDH1A1ALDH3A1ALDH1A3MAPTLMNA | |
| SCHEMBL2298605 | 0.76 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTLMNA | |
| SCHEMBL8171054 | 0.76 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTLMNA | |
| SCHEMBL8171052 | 0.76 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596754-A | Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin | RICOH COMPANY, LTD. (JP) | 1986-06-24 | — | — | US | claimed |
| US-5863683-A | IMPROVED IN BROAD PHOTOSENSITIVE WAVELENGTH RANGE FROM VISIBLE THROUGH NEAR INFRARED, AND CHARGING CHARACTERISTICS ARE STABLE; ORGANIC AND INORGANIC SALT OF ALKALI METALS USED FOR SALT MILLING | RICOH COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |