SCHEMBL8925548

SCHEMBL8925548

CCN(CC)c1ccc(C=Cc2ccc(-c3nnc(-c4ccc(C=Cc5ccc(N(CC)CC)cc5)cc4)o3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.50
KDM4E B2RXH2 6/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 1/20 0.50
ALDH1A1 P00352 9/20 0.49
ALDH3A1 P30838 1/20 0.49
ALDH1A3 P47895 1/20 0.49
MEN1 O00255 7/20 0.46
KMT2A Q03164 7/20 0.46
LMNA P02545 3/20 0.46
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
APP P05067 1/20 0.45
USP2 O75604 3/20 0.45
MAPK1 P28482 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8925543 1.00 MAPT (0.50) MAPTKDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL11571151 0.91 KDM4E (0.64) MAPTKDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL131376 0.90 APP (0.53) MAPTKDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL10402333 0.83 NPC1 (0.59) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL169499 0.83 APP (0.65) MAPTKDM4ECYP3A4ALDH1A1MEN1
SCHEMBL21594514 0.82 ALDH1A1 (0.63) MAPTKDM4ECYP1A2CYP3A4ALDH1A1
SCHEMBL8505384 0.82 TP53 (0.50) MAPTKDM4ECYP1A2CYP3A4ALDH1A1
SCHEMBL8505386 0.82 TP53 (0.50) MAPTKDM4ECYP1A2CYP3A4ALDH1A1
SCHEMBL12313134 0.81 NPC1 (0.53) MAPTKDM4ECYP1A2CYP3A4ALDH1A1
SCHEMBL8171054 0.80 ALDH1A1 (0.71) MAPTKDM4ECYP1A2CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5642188-A APPARATUS COMPRISING LATENT ELECTROSTATIC IMAGE FORMING MEANS, WET DEVELOPMENT MEANS INCLUDING LIQUID DEVELOPER COMPRISING SILICONE OIL CARRIER WITH DISPERSED TONER PARTICLES, IMAGE TRANSFER MEANS, IMAGE FIXING MEANS RICOH COMPANY, LTD. (JP) 1997-06-24 US disclosed
US-5623062-A ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS RICOH COMPANY, LTD. (JP) 1997-04-22 US disclosed
US-5370954-A Photosensitivity, ozone resistance RICOH COMPANY, LTD. (JP) 1994-12-06 US disclosed
EP-0270685-B1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS (JP) 1994-09-07 EP disclosed
US-5344735-A Organic photoconductors, laser printers RICOH COMPANY, LTD. (JP) 1994-09-06 US disclosed
EP-0259099-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-10-13 EP disclosed
US-5219693-A Sensitivity, printing image quality IWATSU ELECTRIC CO., LTD. (JP) 1993-06-15 US disclosed
US-5097022-A Bisazo pigments for use in electrophotographic photoconductors RICOH COMPANY, LTD. (JP) 1992-03-17 US disclosed
US-5081233-A Charge generating compounds RICOH COMPANY, LTD. (JP) 1992-01-14 US disclosed
US-4925758-A AZO PIGMENT AS CHARGE GENERATING COMPOUND RICOH COMPANY, LTD. (JP) 1990-05-15 US disclosed
EP-0270685-A1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-15 EP disclosed
EP-0259099-A2 Electrophotographic photoreceptor MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-09 EP disclosed
US-4716220-A CHARGE CARRIER GENERATING MATERIALS RICOH CO., LTD. (JP) 1987-12-29 US disclosed
US-4708921-A Photosensitive material containing disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1987-11-24 US disclosed
US-4663442-A ELECTROGRAPHY, PHOTOSENSITIVITY RICOH CO., LTD. (JP) 1987-05-05 US disclosed
US-4619878-A Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1986-10-28 US disclosed
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US disclosed
US-4582771-A Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography RICOH CO., LTD. (JP) 1986-04-15 US disclosed
US-4565759-A PHOTOCONDUCTIVE LAYER ON ELECTROCONDUCTIVE SUPPORT RICOH CO., LTD. (JP) 1986-01-21 US disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 US disclosed