Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850591 | 0.86 | F10 (0.48) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL851127 | 0.81 | F10 (0.77) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL8509596 | 0.81 | F10 (0.53) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL851053 | 0.81 | F10 (0.51) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL850827 | 0.78 | F10 (0.57) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL851787 | 0.76 | F2 (0.56) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL6581912 | 0.76 | EGLN1 (0.61) | F10F2EGLN1JAK2JAK1 | |
| SCHEMBL852030 | 0.75 | F10 (0.48) | F10EGLN1SCN9A | |
| SCHEMBL8509642 | 0.74 | F10 (0.58) | F10EGLN1 | |
| SCHEMBL850679 | 0.73 | F10 (0.46) | F10EGLN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-8722930-B2 | Protease inhibitors | ORION CORPORATION (FI) | 2014-05-13 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | F10 152/4885F2 112/4885ST14 216/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | F10 152/4885F2 112/4885ST14 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.