Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406550 | 0.86 | GLA (0.34) | GLASTING1MCL1CYP2D6 | |
| SCHEMBL7824589 | 0.76 | PDCD1 (0.43) | GLASTING1MCL1KDM4ESLC11A2 | |
| SCHEMBL8038419 | 0.74 | HTR1A (0.43) | KDM4ECYP2D6CDK1CCNB1 | |
| SCHEMBL8038415 | 0.73 | ABL1 (0.31) | MCL1 | |
| Hydrochloric Acid SCHEMBL8038029 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8086156 | 0.72 | HTR1A (0.42) | KDM4ECYP2D6CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL8038003 | 0.72 | ABL1 (0.30) | MCL1 | |
| SCHEMBL8081899 | 0.72 | GLA (0.38) | GLASTING1MCL1KDM4ESLC11A2 | |
| SCHEMBL8405997 | 0.71 | — | — | |
| SCHEMBL8406965 | 0.71 | EED (0.37) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888324-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032870-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-09-12 | — | — | WO | disclosed |