SCHEMBL8506993

SCHEMBL8506993

CCCCCC[SiH](Cl)CC(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.40
HTR2A P28223 1/20 0.40
ASAH1 Q13510 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ACER2 Q5QJU3 1/20 0.38
NAAA Q02083 2/20 0.38
AOC3 Q16853 2/20 0.37
TRPA1 O75762 1/20 0.37
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecane SCHEMBL28655501 0.76 TAAR1 (0.50) TAAR1HTR2AASAH1ALDH1A1ACER2
SCHEMBL8506617 0.76 TAAR1 (0.42) TAAR1AOC3TRPA1KCNH2
SCHEMBL1314832 0.75 DNM1 (0.44) KCNH2
SCHEMBL1299997 0.74 RIPK1 (0.52) TAAR1HTR2AASAH1ALDH1A1ACER2
SCHEMBL1412787 0.74 RIPK1 (0.52) TAAR1HTR2AASAH1ALDH1A1ACER2
SCHEMBL16167034 0.74 RIPK1 (0.52) TAAR1HTR2AASAH1ALDH1A1ACER2
SCHEMBL1581397 0.74 RIPK1 (0.52) TAAR1HTR2AASAH1ALDH1A1ACER2
SCHEMBL3080030 0.74 RIPK1 (0.52) TAAR1HTR2AASAH1ALDH1A1ACER2
SCHEMBL9746665 0.74 RIPK1 (0.52) TAAR1HTR2AASAH1ALDH1A1ACER2
SCHEMBL508056 0.74 RIPK1 (0.52) TAAR1HTR2AASAH1ALDH1A1ACER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5965762-A Chlorohydrosilane derivatives and their preparation method KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1999-10-12 US disclosed