Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903747 | 1.00 | RARB (0.35) | RARBSMN1; SMN2PTPN11NFKB1NFKB2 | |
| SCHEMBL8507286 | 0.93 | RARB (0.39) | RARBSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL8507282 | 0.93 | RARB (0.39) | RARBSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL8902962 | 0.87 | CNR2 (0.38) | SMN1; SMN2CNR2CNR1HTTMAPT | |
| SCHEMBL8902970 | 0.87 | CNR2 (0.38) | SMN1; SMN2CNR2CNR1HTTMAPT | |
| SCHEMBL8291242 | 0.86 | NPC1 (0.39) | RARBSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9640876 | 0.84 | RARB (0.43) | RARBPTPN11CNR2CNR1S1PR5 | |
| SCHEMBL9640884 | 0.84 | RARB (0.43) | RARBPTPN11CNR2CNR1S1PR5 | |
| SCHEMBL9618828 | 0.84 | KDM4E (0.47) | RARBSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9618826 | 0.84 | KDM4E (0.47) | RARBSMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5630962-A | 2-Fluoropyridines, their preparation and their use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |