Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 19/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081899 | 0.77 | GLA (0.38) | MTNR1AMTNR1BGLASTING1 | |
| SCHEMBL7824589 | 0.75 | PDCD1 (0.43) | GLASTING1 | |
| SCHEMBL31359145 | 0.71 | NQO2 (0.51) | MTNR1A | |
| SCHEMBL5937268 | 0.71 | NQO2 (0.51) | MTNR1A | |
| SCHEMBL8038419 | 0.70 | HTR1A (0.43) | — | |
| Hydrochloric Acid SCHEMBL8086156 | 0.69 | HTR1A (0.42) | — | |
| SCHEMBL25762901 | 0.68 | GLA (0.35) | GLASTING1 | |
| SCHEMBL11800503 | 0.67 | NQO2 (0.50) | MTNR1A | |
| SCHEMBL11788148 | 0.66 | NQO2 (0.49) | MTNR1A | |
| SCHEMBL21914136 | 0.65 | MGLL (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888324-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032870-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-09-12 | — | — | WO | disclosed |