Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284598 | 0.90 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL14495122 | 0.86 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9828028 | 0.86 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7835759 | 0.85 | MEN1 (0.58) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL10789717 | 0.83 | KMT2A (0.53) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL6628602 | 0.83 | POLB (0.61) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL5841291 | 0.83 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7834034 | 0.83 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8349871 | 0.82 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL5665005 | 0.82 | CTNNB1 (0.65) | MEN1KMT2AALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784619-B1 | PHENYL-OXO-ALKYL-(4-PIPERIDINYL)BENZOATE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1999-03-24 | — | — | EP | disclosed |
| US-5872131-A | Phenyl-oxo-alkyl-(4-piperidinyl)benzoate derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 1999-02-16 | — | — | US | disclosed |
| US-4841047-A | ANTIALLERGENS | AASTA PHARMA AG (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0222191-A1 | 4-Benzyl-1-2(H)-phthalazinone derivatives | ASTA Pharma AG (DE) | 1987-05-20 | — | — | EP | disclosed |