Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.54 |
| ▸ | WNT3A | P56704 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.53 |
| ▸ | TUBB | P07437 | 2/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822746 | 0.93 | MAPK1 (0.56) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL10790468 | 0.91 | KMT2A (0.54) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL10789209 | 0.90 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7837299 | 0.90 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9284598 | 0.89 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9829605 | 0.88 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7046987 | 0.88 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7835759 | 0.87 | MEN1 (0.58) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL3137049 | 0.87 | THRA (0.56) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL25238149 | 0.86 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070196834-A1 | Method and system for the generation of large double stranded DNA fragments | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-08-23 | — | — | US | disclosed |
| EP-0199324-B1 | NEW 2,5-DIARYL TETRYHYDROFURANS AND ANALOGS THEREOF AS PAF ANTAGONISTS | MERCK & CO. INC. (US) | 1991-10-02 | — | — | EP | disclosed |
| EP-0322033-A2 | New 2,5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1989-06-28 | — | — | EP | disclosed |
| EP-0154887-B1 | NEW 2,5-DIARYL TETRAHYDROTHIOPHENES AND ANALOGS THEREOF AS PAF-ANTAGONISTS | MERCK & CO. INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0199324-A2 | New 2,5-diaryl tetryhydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1986-10-29 | — | — | EP | disclosed |