SCHEMBL8508143

SCHEMBL8508143

CCc1n[nH]c(O)c1C(=O)c1ccc(S(C)(=O)=O)c(OCCOC)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4969997 0.89 POLB (0.32) POLBMAPT
SCHEMBL27274639 0.85 MCL1 (0.36) POLBMAPT
SCHEMBL7809075 0.84 GNRHR (0.34)
SCHEMBL7802356 0.83 CYP1A2 (0.34) MAPT
SCHEMBL7807414 0.82 PTGS2 (0.32)
SCHEMBL8508216 0.81
SCHEMBL7811703 0.80
SCHEMBL8506103 0.79
SCHEMBL8303044 0.77 FABP3 (0.33) MAPT
SCHEMBL8304177 0.77 FABP4 (0.38) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0928288-A1 PROCESS FOR PREPARING 1-ALKYL-4- (2-CHLORO-3-ALKOXY-4-ALKYLSULFONYLBENZOYL) -5-HYDROXYPYRAZOLE AND RELATED COMPOUNDS Dow AgroSciences LLC (US) 1999-07-14 EP disclosed
WO-1998042677-A1 PROCESS FOR PREPARING 1-ALKYL-4- (2-CHLORO-3-ALKOXY-4-ALKYLSULFONYLBENZOYL) -5-HYDROXYPYRAZOLE AND RELATED COMPOUNDS DOW AGROSCIENCES LLC (US) 1998-10-01 WO disclosed