Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | TEC | P42680 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509853 | 0.84 | MGMT (0.50) | DHFRMPONUDT1MEN1KMT2A | |
| SCHEMBL6266136 | 0.83 | NUDT1 (0.66) | DHFRMPONUDT1MAOBLMNA | |
| SCHEMBL14383624 | 0.77 | NUDT1 (0.42) | DHFRMPONUDT1HRH4 | |
| SCHEMBL2749327 | 0.76 | SMN1; SMN2 (0.51) | DHFRNUDT1HSP90AB1MEN1KMT2A | |
| SCHEMBL31141585 | 0.76 | SMN1; SMN2 (0.51) | DHFRNUDT1HSP90AB1MEN1KMT2A | |
| SCHEMBL24755030 | 0.75 | SMN1; SMN2 (0.69) | DHFRNUDT1HSP90AB1MEN1KMT2A | |
| SCHEMBL21513508 | 0.75 | SMN1; SMN2 (0.50) | DHFRNUDT1HSP90AB1MEN1KMT2A | |
| SCHEMBL24895914 | 0.75 | SMN1; SMN2 (0.54) | DHFRMPONUDT1HSP90AB1MEN1 | |
| SCHEMBL3930094 | 0.74 | NUDT1 (0.62) | MPONUDT1HSP90AB1MEN1KMT2A | |
| SCHEMBL23764904 | 0.72 | NUDT1 (0.52) | NUDT1HSP90AB1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929046-A | Pyrimidine and purine derivatives and their use in treating tumour cells | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |