Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31141585 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL24755030 | 0.86 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL21513508 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL24895914 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL3930094 | 0.86 | NUDT1 (0.62) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL24755714 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL23764904 | 0.82 | NUDT1 (0.52) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL2750032 | 0.81 | NUDT1 (0.54) | SMN1; SMN2ALDH1A1RAB9ANUDT1MAOB | |
| SCHEMBL22086888 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 | |
| SCHEMBL21160445 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1RAB9ANUDT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-15 | — | — | US | disclosed |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-01 | — | — | US | disclosed |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-09-11 | — | — | US | disclosed |
| US-12344594-B2 | Red-shifted fluorophores | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-07-01 | — | — | US | disclosed |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-04-10 | — | — | US | disclosed |
| US-20210382060-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | Shanghai Glory Capital Management Ltd. (CN) | 2021-12-09 | — | — | US | disclosed |
| US-20210171490-A1 | RED-SHIFTED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2021-06-10 | — | — | US | disclosed |
| EP-3489324-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | East China University of Science and Technology (CN) | 2019-05-29 | — | — | EP | disclosed |
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| EP-2748173-B1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECH (CH) | 2016-11-23 | — | — | EP | disclosed |
| US-9346957-B2 | Cell permeable, fluorescent dye | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20140349282-A1 | Cell Permeable, Fluorescent Dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-11-27 | — | — | US | disclosed |
| EP-2748173-A1 | CELL PERMEABLE, FLUORESCENT DYE | Ecole Polytechnique Federale De Lausanne (EPFL) EPFL-TTO (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013029650-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2013-03-07 | — | — | WO | disclosed |
| US-8178314-B2 | Pyrimidines reacting with O6-alkylguanine-DNA alkyltransferase fusion protein and method for detecting protein | COVALYS BIOSCIENCES AG (CH) | 2012-05-15 | — | — | US | disclosed |
| US-20090186373-A1 | Pyrimidines reacting with O6-Alkylguanine-DNA alkyltransferase | COVALYS BIOSCIENCES AG (CH) | 2009-07-23 | — | — | US | disclosed |
| WO-2009060065-A1 | METHOD OF QUANTIFYING TRANSIENT INTERACTIONS BETWEEN PROTEINS | COVALYS BIOSCIENCES AG (CH) | 2009-05-14 | — | — | WO | disclosed |
| EP-1874738-A1 | PYRIMIDINES REACTING WITH O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | Covalys Biosciences AG (CH) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114409-A9 | PYRIMIDINES REACTING WITH O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | COVALYS BIOSCIENCES AG (CH) | 2007-10-18 | — | — | WO | disclosed |
| WO-2006114409-A1 | PYRIMIDINES REACTING WITH O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | COVALYS BIOSCIENCES AG (CH) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344594-B2 | Red-shifted fluorophores | TFEB, DDX21, CDC73 | SMN1; SMN2 1661/4885ALDH1A1 1847/4885RAB9A 465/4885 |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | TFEB, DDX21, CDC73 | SMN1; SMN2 1659/4885ALDH1A1 1850/4885RAB9A 465/4885 |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | MSN, CHN2, EFHD2 | SMN1; SMN2 1544/4885ALDH1A1 3618/4885RAB9A 329/4885 |
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | AOC2, H1-2, CHAT | SMN1; SMN2 2233/4885ALDH1A1 2761/4885RAB9A 1568/4885 |
| US-20090186373-A1 | Pyrimidines reacting with O6-Alkylguanine-DNA alkyltransferase | HPRT1, UNG, DPYD | SMN1; SMN2 4497/4885ALDH1A1 468/4885RAB9A 3571/4885 |
| US-20210171490-A1 | RED-SHIFTED FLUOROPHORES | TFEB, DDX21, CDC73 | SMN1; SMN2 1661/4885ALDH1A1 1847/4885RAB9A 465/4885 |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | PFAS, FLI1, ARFGEF1 | SMN1; SMN2 4303/4885ALDH1A1 1109/4885RAB9A 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.