Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824162 | 0.83 | TSHR (0.35) | TSHRHTR6 | |
| SCHEMBL6824618 | 0.70 | NR1H4 (0.36) | TSHR | |
| SCHEMBL5397834 | 0.67 | ALDH1A1 (0.50) | TSHRMPO | |
| SCHEMBL29502702 | 0.67 | ALDH1A1 (0.50) | TSHRMPO | |
| SCHEMBL6824158 | 0.65 | DRD3 (0.52) | — | |
| SCHEMBL29937263 | 0.65 | PTPN1 (0.33) | — | |
| SCHEMBL23271976 | 0.63 | SMN1; SMN2 (0.44) | TSHRMPO | |
| SCHEMBL30003031 | 0.63 | SMN1; SMN2 (0.44) | TSHRMPO | |
| SCHEMBL7875810 | 0.63 | MPO (0.45) | TSHRMPO | |
| SCHEMBL19616950 | 0.61 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032112-A1 | METHOD FOR TREATING DIABETES | ELI LILLY AND COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |