Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | PPOX | P50336 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984849 | 0.89 | KMT2A (0.57) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10980211 | 0.88 | KMT2A (0.59) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10990765 | 0.87 | TDP1 (0.55) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9017263 | 0.85 | KMT2A (0.53) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11007482 | 0.84 | MEN1 (0.48) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9854877 | 0.81 | TDP1 (0.55) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9740010 | 0.80 | MEN1 (0.48) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL8694365 | 0.78 | TDP1 (0.74) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10706908 | 0.78 | TDP1 (0.74) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10769585 | 0.77 | TDP1 (0.60) | TDP1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572093-B1 | Herbicidal 2,6-substituted pyridines | SHELL INT RESEARCH (NL) | 1999-04-14 | — | — | EP | disclosed |