Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | PPOX | P50336 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509302 | 0.81 | TDP1 (0.59) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10980211 | 0.81 | KMT2A (0.59) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10990765 | 0.80 | TDP1 (0.55) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10984849 | 0.80 | KMT2A (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9744275 | 0.77 | PIN1 (0.33) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10698436 | 0.77 | MEN1 (0.43) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9017263 | 0.77 | KMT2A (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9743913 | 0.76 | PKM (0.42) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9740010 | 0.74 | MEN1 (0.48) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11007482 | 0.73 | MEN1 (0.48) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453065-A1 | Triazolopyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |