Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017176 | 0.81 | MEN1 (0.60) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL8509302 | 0.80 | TDP1 (0.59) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10980211 | 0.80 | KMT2A (0.59) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10984849 | 0.79 | KMT2A (0.57) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10990765 | 0.77 | TDP1 (0.55) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL11007482 | 0.76 | MEN1 (0.48) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL9017263 | 0.75 | KMT2A (0.53) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL9854877 | 0.74 | TDP1 (0.55) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL11347907 | 0.73 | MEN1 (0.62) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL10454658 | 0.72 | MEN1 (0.62) | MEN1KMT2ATTRPPOXTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5133798-A | Certain herbicidal 1,2,4-triazolo[4,5-b]pyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-28 | — | — | US | disclosed |
| EP-0453065-A1 | Triazolopyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |