Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332859 | 0.87 | LMNA (0.54) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL8814469 | 0.84 | LMNA (0.50) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL5484421 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL5484420 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8667841 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAKDM4EKMT2AMAPT | |
| SCHEMBL28489419 | 0.79 | LMNA (0.55) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL30018340 | 0.79 | LMNA (0.55) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL371082 | 0.77 | LMNA (0.46) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL9852571 | 0.76 | LMNA (0.51) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL333577 | 0.76 | LMNA (0.45) | SMN1; SMN2LMNATSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862420-A4 | SYNTHESIS OF DRUG NANOPARTICLES BY SPRAY DRYING | PENN STATE RES FOUND (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0862420-A1 | SYNTHESIS OF DRUG NANOPARTICLES BY SPRAY DRYING | THE PENN STATE RESEARCH FOUNDATION (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997013503-A1 | SYNTHESIS OF DRUG NANOPARTICLES BY SPRAY DRYING | THE PENN STATE RESEARCH FOUNDATION (US) | 1997-04-17 | — | — | WO | disclosed |