Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814469 | 0.97 | LMNA (0.50) | LMNAALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL28489419 | 0.91 | LMNA (0.55) | LMNAALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL30018340 | 0.91 | LMNA (0.55) | LMNAALDH1A1TSHRKDM4ETP53 | |
| Ethyl Cartrizoate SCHEMBL2110540 | 0.89 | LMNA (0.47) | LMNAALDH1A1TSHRKDM4ETP53 | |
| Mannitol SCHEMBL8510041 | 0.87 | SMN1; SMN2 (0.60) | LMNAALDH1A1TSHRKDM4ETP53 | |
| Benzoic Acid SCHEMBL9410598 | 0.86 | KDM4E (0.49) | LMNAALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL8752047 | 0.86 | LMNA (0.44) | LMNAALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL9016334 | 0.85 | LMNA (0.53) | LMNAALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL8230945 | 0.85 | LMNA (0.53) | LMNAALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL371082 | 0.85 | LMNA (0.46) | LMNAALDH1A1TSHRKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275094-A2 | Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions | Elan Pharma International Limited (IE) | 2011-01-19 | — | — | EP | claimed |
| US-20090081297-A1 | Use of surface tension reducing agents in aerosol formulations | MAP PHARMACEUTICALS, INC. | 2009-03-26 | — | — | US | claimed |
| US-20050265923-A1 | Embolus therapy using insoluble microparticles or vesicles containing contrast agents | TONER JOHN L | 2005-12-01 | — | — | US | claimed |
| US-20050258288-A1 | High pressure media milling system and process of forming particles | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-11-24 | — | — | US | claimed |
| WO-2005053851-A1 | HIGH PRESSURE MEDIA MILLING SYSTEM AND PROCESS OF MILLING PARTICLES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-16 | — | — | WO | claimed |
| EP-0810855-B1 | POLYALKYLENE BLOCK COPOLYMERS AS SURFACE MODIFIERS FOR NANOPARTICLES | ELAN PHARMA INT LTD (IE) | 2003-06-11 | — | — | EP | claimed |
| EP-0804161-B1 | CONTINUOUS METHOD OF GRINDING PHARMACEUTICAL SUBSTANCES | ELAN PHARMA INT LTD (IE) | 2001-11-07 | — | — | EP | claimed |
| EP-0804162-B1 | BUTYLENE OXIDE-ETHYLENE OXIDE BLOCK COPOLYMER SURFACTANTS AS STABILIZER COATINGS FOR NANOCRYSTAL FORMULATION | ELAN PHARMA INT LTD (IE) | 2001-09-05 | — | — | EP | claimed |
| EP-0499299-B1 | Surface modified drug nanoparticles | NANOSYSTEMS LLC (US) | 2000-08-16 | — | — | EP | claimed |
| EP-0600528-B1 | Method of grinding pharmaceutical substances | ELAN PHARMA INTERNATIONAL LIMI (IE) | 2000-06-07 | — | — | EP | claimed |
| EP-0602700-A2 | Novel formulations for nanoparticulate X-ray blood pool contrast agents using high molecular weight surfactants | NanoSystems L.L.C. (US) | 1994-06-22 | — | — | EP | claimed |
| EP-0601619-A2 | Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization | NanoSystems L.L.C. (US) | 1994-06-15 | — | — | EP | claimed |
| EP-0600528-A1 | Method of grinding pharmaceutical substances | NanoSystems L.L.C. (US) | 1994-06-08 | — | — | EP | claimed |
| EP-0600532-A2 | Use of ionic cloud point modifiers to prevent particle aggregation during sterilization | NanoSystems L.L.C. (US) | 1994-06-08 | — | — | EP | claimed |
| US-5318768-A | For gastrointestinal tract; film membrane, cation potentiator, particle surface modifier | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | claimed |
| US-5318767-A | X-ray contrast compositions useful in medical imaging | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | claimed |
| US-5298262-A | Nonionic surfactant particles | STERLING WINTHROP INC. (US) | 1994-03-29 | — | — | US | claimed |
| US-5145684-A | SURFACE MODIFIED DRUG NANOPARTICLES | STERLING DRUG INC. (US) | 1992-09-08 | — | — | US | claimed |
| EP-0499299-A2 | Surface modified drug nanoparticles | NanoSystems L.L.C. (US) | 1992-08-19 | — | — | EP | claimed |
| EP-0498482-A2 | X-ray contrast compositions useful in medical imaging | NanoSystems L.L.C. (US) | 1992-08-12 | — | — | EP | claimed |