Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 7/20 | 0.70 |
| ▸ | MMP1 | P03956 | 10/20 | 0.63 |
| ▸ | MMP2 | P08253 | 7/20 | 0.63 |
| ▸ | MMP3 | P08254 | 6/20 | 0.63 |
| ▸ | MMP8 | P22894 | 5/20 | 0.61 |
| ▸ | MMP9 | P14780 | 4/20 | 0.61 |
| ▸ | MMP7 | P09237 | 2/20 | 0.61 |
| ▸ | FCER2 | P06734 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400674 | 0.90 | PSMB5 (0.69) | PSMB5MMP1MMP2MMP3MMP8 | |
| SCHEMBL15692341 | 0.90 | PSMB5 (0.69) | PSMB5MMP2MMP9MMP7 | |
| SCHEMBL15692320 | 0.90 | PSMB5 (0.73) | PSMB5MMP2MMP9MMP7 | |
| SCHEMBL989841 | 0.90 | PSMB5 (0.64) | PSMB5MMP1MMP2MMP3MMP8 | |
| SCHEMBL15759462 | 0.90 | PSMB5 (0.64) | PSMB5MMP1MMP2MMP3MMP8 | |
| SCHEMBL7403731 | 0.89 | MMP1 (0.61) | PSMB5MMP1MMP2MMP3MMP8 | |
| SCHEMBL6416478 | 0.87 | MMP1 (0.64) | PSMB5MMP1MMP2MMP3MMP8 | |
| SCHEMBL7404527 | 0.85 | MMP1 (0.65) | PSMB5MMP1MMP2MMP3MMP8 | |
| SCHEMBL8015471 | 0.84 | ACE (0.63) | PSMB5MMP1MMP2MMP3MMP8 | |
| SCHEMBL12957256 | 0.84 | PSMB5 (0.62) | PSMB5MMP2MMP3MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981491-A | PEPTIDES; METALLOENZYMES; TUMOR NECROSIS FACTOR | DARWIN DISCOVERY LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |