SCHEMBL989841

SCHEMBL989841

CCCC(=O)NC(Cc1ccccc1)C(=O)NC

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.64
MMP1 P03956 12/20 0.60
CHRNB2 P17787 1/20 0.60
CHRNB4 P30926 1/20 0.60
CHRNA3 P32297 1/20 0.60
CHRNA4 P43681 1/20 0.60
FCER2 P06734 1/20 0.60
MMP3 P08254 12/20 0.59
MMP8 P22894 1/20 0.59
MMP2 P08253 16/20 0.57
MMP7 P09237 6/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15759462 1.00 PSMB5 (0.64) PSMB5MMP1CHRNB2CHRNB4CHRNA3
SCHEMBL8468711 0.90 PSMB5 (0.66) PSMB5MMP1MMP3MMP2MMP7
SCHEMBL8510052 0.90 PSMB5 (0.70) PSMB5MMP1FCER2MMP3MMP8
SCHEMBL7066966 0.88 MMP1 (0.61) MMP1FCER2MMP3MMP8MMP2
SCHEMBL7066963 0.88 MMP1 (0.61) MMP1FCER2MMP3MMP8MMP2
SCHEMBL987191 0.88 PSMB5 (0.64) PSMB5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL25139508 0.88 MMP1 (0.63) PSMB5MMP1FCER2MMP3MMP8
SCHEMBL25000564 0.88 MMP1 (0.63) PSMB5MMP1FCER2MMP3MMP8
SCHEMBL988507 0.87 CHRNB2 (0.65) PSMB5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL15692406 0.87 PSMB5 (0.66) PSMB5CHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180878-A1 AMIDE DERIVATIVES OF BUTYRIC ACID FOR USE IN THE TREATMENT OR PREVENTION OF SARS-COV-2 INFECTION RHEA INNOVATIONS S.R.L. (IT) 2024-06-06 US claimed
EP-4322935-A1 AMIDE DERIVATIVES OF BUTYRIC ACID FOR USE IN THE TREATMENT OR PREVENTION OF SARS-COV-2 INFECTION Rhea Innovations S.R.L. (IT) 2024-02-21 EP claimed
WO-2022219020-A1 AMIDE DERIVATIVES OF BUTYRIC ACID FOR USE IN THE TREATMENT OR PREVENTION OF SARS-COV-2 INFECTION RHEA INNOVATIONS S.R.L. (IT) 2022-10-20 WO claimed
US-10034937-B2 Synergistic nutritional compositions and uses thereof MEAD JOHNSON NUTRITION COMPANY (US) 2018-07-31 US claimed
US-20170215464-A1 NUTRITIONAL COMPOSITIONS CONTAINING DIETARY BUTYRATE AND USES THEREOF MEAD JOHNSON NUTRITION COMPANY 2017-08-03 US claimed
US-20170157242-A1 SYNERGISTIC NUTRITIONAL COMPOSITIONS AND USES THEREOF MEAD JOHNSON NUTRITION COMPANY 2017-06-08 US claimed
US-20170127693-A1 NUTRITIONAL COMPOSITIONS CONTAINING BUTYRATE AND USES THEREOF MEAD JOHNSON NUTRITION COMPANY 2017-05-11 US claimed
US-9255062-B2 Fatty acid derivatives for oral administration endowed with high palatability RHEA INNOVATIONS S.R.L. (IT) 2016-02-09 US claimed
EP-2268605-B1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY BERNI CANANI ROBERTO (IT) 2014-06-04 EP claimed
US-20110098319-A1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY RHEA INNOVATIONS S.R.L. (IT) 2011-04-28 US claimed
EP-2268605-A1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PAIA- TABILITY Berni Canani, Roberto (IT) 2011-01-05 EP claimed
WO-2009130735-A1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY BERNI CANANI ROBERTO (IT) 2009-10-29 WO claimed
WO-2026099710-A1 NUTRITIONAL COMPOSITION AND THERAPEUTIC OR PREVENTIVE USE THEREOF NUTRITECHLAB S.R.L.S. (IT) 2026-05-15 WO disclosed
US-20240180878-A1 AMIDE DERIVATIVES OF BUTYRIC ACID FOR USE IN THE TREATMENT OR PREVENTION OF SARS-COV-2 INFECTION RHEA INNOVATIONS S.R.L. (IT) 2024-06-06 US disclosed
EP-4322935-A1 AMIDE DERIVATIVES OF BUTYRIC ACID FOR USE IN THE TREATMENT OR PREVENTION OF SARS-COV-2 INFECTION Rhea Innovations S.R.L. (IT) 2024-02-21 EP disclosed
WO-2022219020-A1 AMIDE DERIVATIVES OF BUTYRIC ACID FOR USE IN THE TREATMENT OR PREVENTION OF SARS-COV-2 INFECTION RHEA INNOVATIONS S.R.L. (IT) 2022-10-20 WO disclosed
US-9255062-B2 Fatty acid derivatives for oral administration endowed with high palatability RHEA INNOVATIONS S.R.L. (IT) 2016-02-09 US disclosed
EP-2268605-B1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY BERNI CANANI ROBERTO (IT) 2014-06-04 EP disclosed
US-20110098319-A1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY RHEA INNOVATIONS S.R.L. (IT) 2011-04-28 US disclosed
WO-2009130735-A1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY BERNI CANANI ROBERTO (IT) 2009-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098319-A1 FATTY ACID DERIVATIVES FOR ORAL ADMINISTRATION ENDOWED WITH HIGH PALATABILITY FABP2, FFAR2, VIP PSMB5 1845/4885MMP1 4498/4885CHRNB2 1195/4885
US-10034937-B2 Synergistic nutritional compositions and uses thereof FABP2, LRBA, TSLP PSMB5 878/4885MMP1 4634/4885CHRNB2 222/4885
US-20170157242-A1 SYNERGISTIC NUTRITIONAL COMPOSITIONS AND USES THEREOF FABP2, LRBA, TSLP PSMB5 878/4885MMP1 4634/4885CHRNB2 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.