Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 1/20 | 0.52 |
| ▸ | TYMS | P04818 | 4/20 | 0.51 |
| ▸ | TYMP | P19971 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650972 | 1.00 | TK2 (0.52) | TK2TK1TYMSTYMP | |
| SCHEMBL6044983 | 0.94 | TK2 (0.59) | TK2TK1TYMSTYMP | |
| SCHEMBL8655346 | 0.93 | TK2 (0.46) | TK2TK1TYMSTYMP | |
| SCHEMBL8655343 | 0.93 | TK2 (0.46) | TK2TK1TYMSTYMP | |
| SCHEMBL8654230 | 0.88 | TK1 (0.40) | TK2TK1TYMSTYMP | |
| SCHEMBL8654233 | 0.88 | TK1 (0.40) | TK2TK1TYMSTYMP | |
| SCHEMBL8159110 | 0.87 | TYMS (0.46) | TK2TK1TYMSTYMP | |
| SCHEMBL8166332 | 0.87 | TYMS (0.47) | TK2TK1TYMSTYMP | |
| Hexanoate SCHEMBL6563169 | 0.87 | TYMS (0.49) | TK2TK1TYMSTYMP | |
| SCHEMBL22984023 | 0.86 | TYMS (0.56) | TK1TYMSTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923596-A2 | LIPOPHILIC OLIGONUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5763208-A | Oligonucleotides and their analogs capable of passive cell membrane permeation | GILEAD SCIENCES, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1998004575-A2 | LIPOPHILIC OLIGONUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1998-02-05 | — | — | WO | disclosed |
| US-5633360-A | CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES | GILEAD SCIENCES, INC. (US) | 1997-05-27 | — | — | US | disclosed |