SCHEMBL8510246

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17315853	0.85	RAB9A (0.59)	NPC1RAB9AATMKMT2AL3MBTL1
	SCHEMBL4449131	0.82	NPC1 (0.56)	NPC1RAB9ANR0B1ATMMEN1
	SCHEMBL5631579	0.79	NPC1 (0.55)	NPC1RAB9ANR0B1ATMMEN1
	SCHEMBL1652624	0.77	NPC1 (0.61)	NPC1RAB9ANR0B1ATMMEN1
	SCHEMBL16303154	0.75	NPC1 (0.52)	NPC1RAB9ANR0B1ATMMEN1
	SCHEMBL6361946	0.75	RAB9A (0.58)	NPC1RAB9ANR0B1ATMMEN1
	SCHEMBL2601270	0.75	NPC1 (0.52)	NPC1RAB9ANR0B1ATMMEN1
	SCHEMBL8079170	0.74	HTT (0.55)	NPC1RAB9AKMT2ATDP1L3MBTL1
	SCHEMBL30585557	0.74	KDM4E (0.50)	NPC1RAB9AATMKMT2ATDP1
	SCHEMBL11770261	0.73	RAB9A (0.48)	NPC1RAB9ANR0B1ATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.