Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5242033 | 0.93 | HTT (0.49) | HTTLMNATDP1KDM4EMAPT | |
| SCHEMBL28269774 | 0.78 | L3MBTL1 (0.49) | TDP1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL2491687 | 0.78 | LMNA (0.63) | HTTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL4461476 | 0.78 | RXFP1 (0.42) | HTTLMNATDP1KDM4EMAPT | |
| SCHEMBL4360862 | 0.77 | NPC1 (0.72) | HTTLMNAKDM4EMAPTNPC1 | |
| SCHEMBL15293589 | 0.76 | NPC1 (0.51) | LMNATDP1RXFP1NPC1RAB9A | |
| SCHEMBL17315853 | 0.76 | RAB9A (0.59) | HTTLMNAKDM4EMAPTNPC1 | |
| SCHEMBL11724643 | 0.76 | LMNA (0.50) | HTTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL8510246 | 0.74 | NPC1 (0.51) | HTTTDP1KDM4EMAPTNPC1 | |
| SCHEMBL10031570 | 0.74 | L3MBTL1 (0.75) | KDM4EMAPTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026182-A1 | FOUR COMPONENT COPOLYMER AND THE OCULAR LENS MADE THEREOF | SANTEN PHARMACEUTICAL CO., LTD (JP) | 2000-08-09 | — | — | EP | disclosed |