SCHEMBL8510347

SCHEMBL8510347

C=CCCCCCCCCc1ccsc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.47
TDP1 Q9NUW8 2/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC4 P56524 1/20 0.41
NAAA Q02083 1/20 0.40
DRD2 P14416 1/20 0.40
DRD3 P35462 1/20 0.40
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34
GLS O94925 1/20 0.33
GPR52 Q9Y2T5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034032 1.00 TAAR1 (0.47) TAAR1TDP1USP2ALDH1A1HPGD
SCHEMBL27848962 0.98 TAAR1 (0.48) TAAR1TDP1USP2ALDH1A1HPGD
SCHEMBL867604 0.92 TAAR1 (0.50) TAAR1TDP1USP2ALDH1A1HPGD
SCHEMBL10765524 0.84
SCHEMBL10521145 0.84 TAAR1 (0.62) TAAR1ALDH1A1NAAADRD2DRD3
SCHEMBL9855401 0.82 TAAR1 (0.65) TAAR1ALDH1A1NAAADRD2DRD3
SCHEMBL7293984 0.81 TAAR1 (0.47) TAAR1ALDH1A1HPGDNAAADRD2
SCHEMBL4556686 0.81 ALDH1A1 (0.44) ALDH1A1NAAATSHRLMNA
SCHEMBL2091328 0.79 TAAR1 (0.52) TAAR1ALDH1A1HDAC1NAAADRD2
SCHEMBL16289598 0.79 TAAR1 (0.52) TAAR1ALDH1A1HDAC1NAAADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587159-B1 3-Thienyl silicon compounds, chemically adsorbed ultrathin film formed therefrom and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1999-06-23 EP disclosed
US-5461166-A Chemically adsorbed ultrathin film and its material, and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1995-10-24 US disclosed
EP-0587159-A1 3-Thienyl silicon compounds, chemically adsorbed ultrathin film formed therefrom and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1994-03-16 EP disclosed