Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976898 | 0.97 | TSHR (0.39) | TSHRACHELMNAALOX12APOBEC3A | |
| Phosphonic Acid SCHEMBL23704360 | 0.81 | NPSR1 (0.32) | TSHROPRM1OPRL1ALDH1A1MEN1 | |
| SCHEMBL2968167 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL15771658 | 0.73 | TSHR (0.37) | TSHRACHELMNAALOX12APOBEC3A | |
| Hydrochloric Acid SCHEMBL6906610 | 0.73 | TSHR (0.37) | TSHRACHELMNAALOX12APOBEC3A | |
| Bromide SCHEMBL15772385 | 0.73 | TSHR (0.37) | TSHRACHELMNAALOX12APOBEC3A | |
| SCHEMBL9747871 | 0.71 | — | — | |
| SCHEMBL1624424 | 0.69 | — | — | |
| SCHEMBL2166400 | 0.69 | ALDH1A1 (0.35) | TSHRACHELMNAALOX12APOBEC3A | |
| SCHEMBL6437540 | 0.69 | OPRM1 (0.39) | TSHRACHELMNAALOX12APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643366-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORP (US) | 2015-03-25 | — | — | EP | disclosed |
| US-8895465-B2 | Activator compositions, their preparation, and their use in catalysis | ALBEMARLE CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |
| EP-2643366-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | Albemarle Corporation (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20130253155-A1 | Activator Compositions, Their Preparation, and Their Use In Catalysis | ALBEMARIE CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012071205-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORPORATION (US) | 2012-05-31 | — | — | WO | disclosed |
| CN-1043999-C | Bulk polymerization process of butadienes | GOODYEAR TIRE & RUBBER (US) | 1999-07-07 | — | — | CN | disclosed |
| CN-87101920-A | butadiene bulk polymerization process | — | 1987-12-09 | — | — | CN | disclosed |