SCHEMBL851054

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15358609	0.98	RARB (0.56)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL848751	0.93	RARB (0.54)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL14089940	0.85	ALDH1A1 (0.56)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL28873230	0.85	RARB (0.72)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL9472454	0.85	RARB (0.72)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL30053056	0.85	RARB (0.72)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL15583704	0.85	RARB (0.72)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL371605	0.83	RARB (0.71)	RARBALDH1A1MEN1RARAMAPT
	SCHEMBL848808	0.81	FOLH1 (0.50)	ALDH1A1FAAHCES1
	SCHEMBL22721254	0.81	RARB (0.60)	RARBALDH1A1MEN1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.