SCHEMBL8510666

SCHEMBL8510666

O=C1C=CC(=O)N1CO[SiH3]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.48
FAAH O00519 4/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
BLM P54132 2/20 0.48
GMNN O75496 1/20 0.48
THPO P40225 1/20 0.48
PMP22 Q01453 1/20 0.48
HPGD P15428 2/20 0.46
HSP90AA1 P07900 1/20 0.46
TLR9 Q9NR96 1/20 0.46
TP53 P04637 1/20 0.46
PKM P14618 1/20 0.46
XBP1 P17861 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
RECQL P46063 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145760 0.77 MGLL (0.56) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL277926 0.72 MGLL (0.55) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL22264531 0.72 MGLL (0.52) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL14678413 0.69 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL114195 0.69 MGLL (0.58) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL145737 0.69 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL10759118 0.69 ALDH1A1 (0.63) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL28365540 0.69 MGLL (0.56) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL5826263 0.67
SCHEMBL13970279 0.67 MGLL (0.54) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912282-A Die attach adhesive compositions SHELL OIL COMPANY (US) 1999-06-15 US disclosed
US-5840215-A COMPRISING THERMALLY REWORKABLE CROSSLINKED RESIN PRODUCED BY REACTING DIENOPHILE AND 2,5-DIALKYL SUBSTITUTED FURAN-CONTAING POLYMER AND ELECTRICALLY CONDUCTIVE MATERIAL SHELL OIL COMPANY (US) 1998-11-24 US disclosed
US-5760337-A Thermally reworkable binders for flip-chip devices SHELL OIL COMPANY (US) 1998-06-02 US disclosed
US-5726391-A FURAN POLYMER SHELL OIL COMPANY (US) 1998-03-10 US disclosed