Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA9 | Q16790 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507889 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL50583 | 0.85 | TSHR (0.55) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| Water SCHEMBL28012117 | 0.85 | TSHR (0.55) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL447639 | 0.85 | LMNA (0.65) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL525918 | 0.85 | LMNA (0.65) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL3171676 | 0.85 | LMNA (0.65) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL29990536 | 0.85 | LMNA (0.65) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL27450647 | 0.83 | TSHR (0.52) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL2174084 | 0.83 | TSHR (0.52) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL27579780 | 0.83 | TSHR (0.52) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278963-A | The sulfonamides compound of targeting carbonic anhydrase Ⅸ, intermediate and preparation and application | 上海原子科兴药业有限公司 | 2017-01-04 | — | — | CN | disclosed |
| US-5980590-A | HIGH COLOR YIELD; FOR DYEING OR PRINTING OF CELLULOSIC FIBERS, WOOL, AND POLYAMIDE FIBERS | DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1999-11-09 | — | — | US | disclosed |