Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800856 | 0.90 | MAPT (0.46) | LMNASCN5AHRH3CYP1A2MAOA | |
| SCHEMBL16101578 | 0.84 | HRH3 (0.53) | LMNASCN5AHRH3CYP1A2MAOA | |
| SCHEMBL181559 | 0.83 | MAPT (0.52) | LMNASCN5AHRH3CYP1A2MAOA | |
| SCHEMBL8972279 | 0.82 | ALDH1A1 (0.56) | LMNAACHERAB9AMAPTALDH1A1 | |
| SCHEMBL2494993 | 0.82 | MAPT (0.61) | LMNASCN5AHRH3CYP1A2MAOA | |
| SCHEMBL4975464 | 0.81 | MAPT (0.46) | LMNAGAAMAPTALDH1A1AR | |
| SCHEMBL8514565 | 0.81 | APP (0.50) | LMNASCN5AHRH3CYP1A2MAOA | |
| SCHEMBL19035328 | 0.78 | ALDH1A1 (0.41) | LMNASCN5AHRH3CYP1A2MAOA | |
| SCHEMBL17040408 | 0.78 | RARB (0.51) | LMNAHRH3ACHEHTR2AHTR2C | |
| SCHEMBL20692502 | 0.77 | MAPT (0.59) | HRH3GAAABL1HRH4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841471-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | GRACE W R & CO (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20190153135-A1 | Activator Compositions, Their Preparation, And Their Use In Catalysts | GRACE W R & CO (US) | 2019-05-23 | — | — | US | disclosed |
| US-10221264-B2 | Activator compositions, their preparation, and their use in catalysts | W. R. GRACE & CO.-CONN. (US) | 2019-03-05 | — | — | US | disclosed |
| CN-104854150-A | Activator compositions, their preparation, and their use in catalysts | ALBEMARLE CORP | 2015-08-19 | — | — | CN | disclosed |
| US-20150105238-A1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | W. R. GRACE & CO.-CONN. | 2015-04-16 | — | — | US | disclosed |
| EP-2643366-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORP (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-2841471-A1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | Albemarle Corporation (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8895465-B2 | Activator compositions, their preparation, and their use in catalysis | ALBEMARLE CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |
| WO-2013162745-A1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | ALBEMARLE CORPORATION (US) | 2013-10-31 | — | — | WO | disclosed |
| EP-2643366-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | Albemarle Corporation (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20130253155-A1 | Activator Compositions, Their Preparation, and Their Use In Catalysis | ALBEMARIE CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012071205-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORPORATION (US) | 2012-05-31 | — | — | WO | disclosed |