Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39272 | 0.94 | ALDH1A1 (0.50) | APPMAPK1BLMALDH1A1HSD17B10 | |
| SCHEMBL30800856 | 0.90 | MAPT (0.46) | MAPK1BLMALDH1A1GAAMAPT | |
| SCHEMBL45594 | 0.88 | ABL1 (0.49) | APPMAPK1BLMALDH1A1HSD17B10 | |
| SCHEMBL7263389 | 0.86 | ESR1 (0.52) | MAPK1BLMALDH1A1HSD17B10GAA | |
| SCHEMBL1954253 | 0.86 | ESR1 (0.52) | MAPK1BLMALDH1A1HSD17B10GAA | |
| SCHEMBL7262799 | 0.86 | ESR1 (0.52) | MAPK1BLMALDH1A1HSD17B10GAA | |
| SCHEMBL1573489 | 0.86 | ESR1 (0.52) | MAPK1BLMALDH1A1HSD17B10GAA | |
| SCHEMBL1953355 | 0.86 | ESR1 (0.52) | MAPK1BLMALDH1A1HSD17B10GAA | |
| SCHEMBL10485907 | 0.86 | ESR1 (0.52) | MAPK1BLMALDH1A1HSD17B10GAA | |
| SCHEMBL7271147 | 0.86 | ESR1 (0.52) | MAPK1BLMALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841471-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | GRACE W R & CO (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20190153135-A1 | Activator Compositions, Their Preparation, And Their Use In Catalysts | GRACE W R & CO (US) | 2019-05-23 | — | — | US | disclosed |
| US-10221264-B2 | Activator compositions, their preparation, and their use in catalysts | W. R. GRACE & CO.-CONN. (US) | 2019-03-05 | — | — | US | disclosed |
| US-20150105238-A1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | W. R. GRACE & CO.-CONN. | 2015-04-16 | — | — | US | disclosed |
| EP-2643366-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORP (US) | 2015-03-25 | — | — | EP | disclosed |
| US-8895465-B2 | Activator compositions, their preparation, and their use in catalysis | ALBEMARLE CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |
| EP-2643366-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | Albemarle Corporation (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20130253155-A1 | Activator Compositions, Their Preparation, and Their Use In Catalysis | ALBEMARIE CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012071205-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORPORATION (US) | 2012-05-31 | — | — | WO | disclosed |