Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914412 | 0.73 | ALDH1A1 (1.00) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL1892119 | 0.72 | MEN1 (0.63) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL7137961 | 0.71 | LTA4H (0.55) | LMNA | |
| SCHEMBL7137958 | 0.71 | LTA4H (0.55) | LMNA | |
| SCHEMBL8372730 | 0.71 | ALDH1A1 (0.87) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL5805320 | 0.71 | ALDH1A1 (0.87) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8624615 | 0.71 | MEN1 (0.62) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL7320462 | 0.71 | TSHR (0.63) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8481677 | 0.70 | TSHR (0.61) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| Water SCHEMBL8479959 | 0.70 | TSHR (0.61) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958969-A | OSTEOPOROSIS | ELI LILLY AND COMPANY (US) | 1999-09-28 | — | — | US | disclosed |