Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 5/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510596 | 0.89 | F2RL3 (0.41) | F2RL3PDK1PPARAMAPTLMNA | |
| SCHEMBL8513176 | 0.86 | F2RL3 (0.39) | F2RL3PDK1PPARAMAPTLMNA | |
| SCHEMBL8511853 | 0.86 | F2RL3 (0.39) | F2RL3PDK1PPARAMAPK1NPC1 | |
| SCHEMBL8511842 | 0.79 | F2RL3 (0.39) | F2RL3PDK1PPARANPC1 | |
| SCHEMBL8511932 | 0.73 | F2RL3 (0.40) | F2RL3PDK1MAPTLMNAMAPK1 | |
| SCHEMBL8510074 | 0.73 | F2RL3 (0.40) | F2RL3PDK1PPARAMAPTMAPK1 | |
| SCHEMBL8513065 | 0.73 | F2RL3 (0.40) | F2RL3PDK1PPARAMAPTLMNA | |
| SCHEMBL1821962 | 0.72 | F2RL3 (0.43) | F2RL3PDK1PPARAMAPTCSF1R | |
| SCHEMBL1820930 | 0.72 | F2RL3 (0.41) | F2RL3PDK1PPARAMAPTLMNA | |
| SCHEMBL8513075 | 0.71 | ALDH1A1 (0.43) | MAPTLMNAMAPK1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439236-B1 | RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-20120136102-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |