Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510596 | 0.89 | F2RL3 (0.41) | F2RL3MAPTTSHRKDM4ETP53 | |
| SCHEMBL8511734 | 0.86 | F2RL3 (0.40) | F2RL3MAPTALDH1A1KMT2APDK1 | |
| SCHEMBL8511853 | 0.84 | F2RL3 (0.39) | F2RL3TP53ALOX15ALDH1A1PDK1 | |
| SCHEMBL8511932 | 0.81 | F2RL3 (0.40) | F2RL3MAPTTSHRKDM4ETP53 | |
| SCHEMBL1820704 | 0.76 | F2RL3 (0.39) | F2RL3MAPTTSHRKDM4ETP53 | |
| SCHEMBL8511842 | 0.74 | F2RL3 (0.39) | F2RL3PDK1PPARA | |
| SCHEMBL1820157 | 0.73 | F2RL3 (0.40) | F2RL3MAPTALDH1A1PDK1PPARA | |
| SCHEMBL1820930 | 0.72 | F2RL3 (0.41) | F2RL3MAPTALDH1A1PDK1PPARA | |
| SCHEMBL8512794 | 0.72 | ALDH1A1 (0.41) | MAPTTSHRKDM4ETP53ALOX15 | |
| SCHEMBL8510074 | 0.71 | F2RL3 (0.40) | F2RL3MAPTTSHRKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439236-B1 | RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-20120136102-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |