SCHEMBL851189

SCHEMBL851189

NCC(O)CC[C@H](N)[C]=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 3/20 0.36
LMNA P02545 1/20 0.36
GABBR2 O75899 1/20 0.32
GABBR1 Q9UBS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971467 1.00 GABRR1 (0.36) GABRR1LMNAGABBR2GABBR1
SCHEMBL285028 0.81
SCHEMBL497323 0.78
SCHEMBL5427480 0.76 GABRR1 (0.31) GABRR1LMNA
SCHEMBL6901467 0.76 GABRR1 (0.45) GABRR1LMNAGABBR2GABBR1
SCHEMBL11795419 0.75
SCHEMBL7332947 0.72
SCHEMBL27820254 0.71
SCHEMBL381733 0.71
SCHEMBL8633356 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024050285-A2 LEPTIN ANALOGS FOR TREATING OBESITY AND WEIGHT MANAGEMENT THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-03-07 WO disclosed
WO-2024030214-A2 BRINP2-DERIVED PEPTIDE COMPOSITIONS FOR TREATING OBESITY AND WEIGHT MANAGEMENT THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-02-08 WO disclosed
US-20230192767-A1 IL-2RGAMMA BINDING COMPOUNDS MCMEEKIN, DERMOT (GB) 2023-06-22 US disclosed
US-11548914-B2 IL-2Rgamma binding compounds MEDIKINE, INC. (US) 2023-01-10 US disclosed
US-11390657-B2 Peptide analogs ADEPTHERA LLC (US) 2022-07-19 US disclosed
EP-4023667-A1 IL-2 RECEPTOR BINDING COMPOUNDS Medikine, Inc. (US) 2022-07-06 EP disclosed
US-11358986-B2 IL-2RBETA binding compounds MEDIKINE, INC. (US) 2022-06-14 US disclosed
EP-3833679-A1 IL-2 RECEPTOR BINDING COMPOUNDS Medikine, Inc. (US) 2021-06-16 EP disclosed
US-11034745-B2 Superagonist polypeptide analogs of adrenomedullin and intermedin peptide hormones ADEPTHERA LLC (US) 2021-06-15 US disclosed
EP-3294752-B1 PEPTIDE TREATMENT FOR INFLAMMATION AND FIBROSIS UNIV CALIFORNIA (US) 2020-11-04 EP disclosed
CN-1099613-A Method and medical agent for diagnosis and/or therapy of arthritis NIPPON PETROCHEMICALS CO LTD (JP) 1995-03-08 CN disclosed
EP-0629409-A1 Tetrapyrrole carboxylic acid derivatives for diagnosis and/or therapy of arthritis NIPPON PETROCHEMICALS CO., LTD. (JP) 1994-12-21 EP disclosed
US-5308861-A Tetrapyrole compounds NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1994-05-03 US disclosed
EP-0213272-B1 NEW TETRAPYRROLE POLYAMINOMONOCARBOXYLIC ACID THERAPEUTIC AGENTS Nippon Petrochemicals Co., Ltd. (JP) 1992-09-09 EP disclosed
EP-0200218-B1 TETRAPYRROLE THERAPEUTIC AGENTS Nippon Petrochemicals Co., Ltd. (JP) 1992-01-22 EP disclosed
US-4997639-A Porphyrins NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-03-05 US disclosed
EP-0213272-A2 New tetrapyrrole polyaminomonocarboxylic acid therapeutic agents Nippon Petrochemicals Co., Ltd. (JP) 1987-03-11 EP disclosed
EP-0200218-A2 Tetrapyrrole therapeutic agents Nippon Petrochemicals Co., Ltd. (JP) 1986-11-05 EP disclosed
US-4410513-A Synthetic peptides having pituitary growth hormone releasing activity BECKMAN INSTRUMENTS, INC. (US) 1983-10-18 US disclosed
WO-1983002272-A1 SYNTHETIC PEPTIDES HAVING PITUITARY GROWTH HORMONE RELEASING ACTIVITY BECKMAN INSTRUMENTS INC (US) 1983-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11034745-B2 Superagonist polypeptide analogs of adrenomedullin and intermedin peptide hormones RAMP1, CALCRL, RAMP3 GABRR1 2351/4885LMNA 1517/4885GABBR2 2718/4885
US-11390657-B2 Peptide analogs RAMP1, RAMP3, RAMP2 GABRR1 531/4885LMNA 3399/4885GABBR2 820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.