Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | LIPA | P38571 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2696873 | 1.00 | MAPT (0.45) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL2696875 | 0.90 | MAPT (0.41) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL4552150 | 0.88 | MAPT (0.39) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL28358599 | 0.85 | MAPT (0.41) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| Bicarbonate SCHEMBL2763274 | 0.84 | MAPT (0.44) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| Bicarbonate SCHEMBL679005 | 0.84 | MAPT (0.44) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| Bicarbonate SCHEMBL35810 | 0.84 | MAPT (0.44) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL22733770 | 0.83 | MAPT (0.42) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL2380079 | 0.82 | MAPT (0.40) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL28199763 | 0.80 | MAPT (0.51) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421170-B2 | Granulate material and associated coating that is low in odor and emissions, particularly a construction element coating, for example a floor coating, based on a radical polymerization | SIDEC NV (BE) | 2025-09-23 | — | — | US | claimed |
| US-20220220031-A1 | GRANULATE MATERIAL AND ASSOCIATED COATING THAT IS LOW IN ODOR AND EMISSIONS, PARTICULARLY A CONSTRUCTION ELEMENT COATING, FOR EXAMPLE A FLOOR COATING, BASED ON A RADICAL POLYMERIZATION | SIDEC NV (BE) | 2022-07-14 | — | — | US | claimed |
| US-12428559-B2 | Curable compositions and methods of making and using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-09-30 | — | — | US | disclosed |
| US-12421170-B2 | Granulate material and associated coating that is low in odor and emissions, particularly a construction element coating, for example a floor coating, based on a radical polymerization | SIDEC NV (BE) | 2025-09-23 | — | — | US | disclosed |
| EP-4377367-A1 | COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, AN ALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLE AND METHOD | 3M Innovative Properties Company (US) | 2024-06-05 | — | — | EP | disclosed |
| EP-4244267-A1 | FREE-RADICALLY POLYMERIZABLE CROSSLINKER, CURABLE COMPOSITION, AND ADHESIVE THEREFROM | 3M Innovative Properties Company (US) | 2023-09-20 | — | — | EP | disclosed |
| EP-4244268-A1 | FREE-RADICALLY POLYMERIZABLE CROSSLINKER, CURABLE COMPOSITION, AND ADHESIVE THEREFROM | 3M Innovative Properties Company (US) | 2023-09-20 | — | — | EP | disclosed |
| WO-2023166342-A1 | POLYMERIZABLE COMPOSITIONS INCLUDING A POLYMERIZABLE COMPONENT AND A REDOX INITIATION SYSTEM CONTAINING A PHOTOLABILE REDUCING AGENT, AND A PHOTOLABILE REDUCING AGENT | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-09-07 | — | — | WO | disclosed |
| US-20230082209-A1 | LIGHT AND REDOX CURABLE COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2023-03-16 | — | — | US | disclosed |
| WO-2023007401-A1 | COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, AN ALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLE AND METHOD | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-02-02 | — | — | WO | disclosed |
| US-20220372290-A1 | CURABLE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2022-11-24 | — | — | US | disclosed |
| EP-1170815-B1 | Battery | SONY CORP (JP) | 2006-09-27 | — | — | EP | disclosed |
| US-7074522-B2 | Battery | SONY CORPORATION (JP) | 2006-07-11 | — | — | US | disclosed |
| CN-1501542-A | Lithium secondary battery and a method for preparing the same | 三星SDI株式会社 | 2004-06-02 | — | — | CN | disclosed |
| US-20020076617-A1 | Wherein deterioration is prevented via using a metal foil electroconductive layer other than copper (nickel, chromium), thereby controlling polymerization | SONY CORPORATION (JP) | 2002-06-20 | — | — | US | disclosed |
| EP-1170815-A2 | Battery | SONY CORPORATION (JP) | 2002-01-09 | — | — | EP | disclosed |
| CN-1126137-A | Process for preparing colour contrasts on aticles obtained by molding from polymerizable compositions | ATOHAAS HOLDING CV (NL) | 1996-07-10 | — | — | CN | disclosed |
| US-4551369-A | TOILET SEAT SUPPORT | RB KUNSTSTOFFPATENT-VERWERTUNGS AG, WESTBAHNHOFSTRASSE, 11 CH-4500 SOLOTHURN, GERMANY A CORP. OF GERMANY | 1985-11-05 | — | — | US | disclosed |
| EP-0037778-B1 | 2-(1,4-BENZODIOXANYL)-METHOXY-PROPANOL AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | PIERRE FABRE S.A. (FR) | 1983-12-28 | — | — | EP | disclosed |
| EP-0037778-A1 | 2-(1,4-Benzodioxanyl)-methoxy-propanol amines, process for their preparation and their use as medicines | PIERRE FABRE S.A. (FR) | 1981-10-14 | — | — | EP | disclosed |