Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 1.00 |
| ▸ | CA1 | P00915 | 5/20 | 1.00 |
| ▸ | CA9 | Q16790 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393962 | 0.82 | CA12 (1.00) | CA12CA1CA9CYP3A4CYP2A6 | |
| SCHEMBL8515316 | 0.82 | CA12 (1.00) | CA12CA1CA9CYP3A4CYP2A6 | |
| SCHEMBL6560676 | 0.75 | CA12 (0.60) | CA12CA1CA9CYP3A4CYP2A6 | |
| SCHEMBL8535505 | 0.74 | CA12 (0.58) | CA12CA1CA9CYP3A4CYP2A6 | |
| SCHEMBL3820950 | 0.70 | HPGD (0.54) | CA12CA1CA9CYP3A4CYP2A6 | |
| SCHEMBL16470197 | 0.70 | CA12 (0.54) | CA12CA1CA9CYP3A4CYP2A6 | |
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.68 | HPGD (0.60) | CA12CA1CA9CYP3A4CYP2A6 | |
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.68 | HPGD (0.60) | CA12CA1CA9CYP3A4CYP2A6 | |
| SCHEMBL3913263 | 0.68 | CA12 (0.74) | CA12CA1CA9CYP3A4CYP2A6 | |
| SCHEMBL3328856 | 0.67 | MAOA (0.56) | CA12CA1CA9CYP3A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771488-B1 | CARBONIC ANHYDRASE IX-RELATED MARKERS AND USE THEREOF | SIGNALCHEM LIFESCIENCES CORP (CA) | 2018-03-28 | — | — | EP | claimed |
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | claimed |
| WO-2012070024-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2012-05-31 | — | — | WO | claimed |
| EP-2771488-B1 | CARBONIC ANHYDRASE IX-RELATED MARKERS AND USE THEREOF | SIGNALCHEM LIFESCIENCES CORP (CA) | 2018-03-28 | — | — | EP | disclosed |
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | disclosed |
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | disclosed |
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | disclosed |
| WO-2012070024-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012070024-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | CA7, CA4, CA2 | CA12 10/4885CA1 5/4885CA9 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.