Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9943686 | 0.99 | SIGMAR1 (0.56) | SIGMAR1SCN8ATBXA2RTBXAS1MAPK14 | |
| SCHEMBL9882928 | 0.92 | SIGMAR1 (0.46) | SIGMAR1SCN8ATBXA2RTBXAS1MAPK14 | |
| Hydrochloric Acid SCHEMBL8514832 | 0.91 | SIGMAR1 (0.45) | SIGMAR1SCN8ATBXA2RTBXAS1MAPK14 | |
| SCHEMBL8512433 | 0.85 | SIGMAR1 (0.61) | SIGMAR1MAOACHRM2ALDH1A1 | |
| SCHEMBL9882970 | 0.84 | SIGMAR1 (0.53) | SIGMAR1SCN8AMAOACHRM2SLC6A5 | |
| Hydrochloric Acid SCHEMBL8515244 | 0.83 | SIGMAR1 (0.52) | SIGMAR1SCN8AMAOASLC6A5GAA | |
| SCHEMBL9882956 | 0.82 | SIGMAR1 (0.61) | SIGMAR1TBXA2RTBXAS1MAOACHRM2 | |
| Hydrochloric Acid SCHEMBL8529048 | 0.81 | SIGMAR1 (0.59) | SIGMAR1TBXA2RTBXAS1MAOACHRM2 | |
| SCHEMBL9882944 | 0.80 | SCN8A (0.50) | SIGMAR1SCN8AMAOACHRM2SLC6A5 | |
| Hydrochloric Acid SCHEMBL8512445 | 0.79 | SCN8A (0.49) | SIGMAR1SCN8AMAOACHRM2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2013-11-07 | — | — | US | disclosed |
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2013-11-07 | — | — | US | disclosed |
| EP-2642987-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | Faes Farma, S.A. (ES) | 2013-10-02 | — | — | EP | disclosed |
| EP-2465498-A1 | Diphenyl-amine derivatives: uses, process of synthesis and pharmaceutical compositions | FAES FARMA, S.A. (ES) | 2012-06-20 | — | — | EP | disclosed |
| WO-2012069442-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069442-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | CYP2D6, DDC, PAH | SIGMAR1 1329/4885SCN8A 2511/4885TBXA2R 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.