Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | EPOR | P19235 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513717 | 1.00 | CPB2 (0.43) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL28720460 | 0.85 | CPB2 (0.44) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL7593236 | 0.78 | CPB2 (0.49) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL7593232 | 0.78 | CPB2 (0.49) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL468723 | 0.76 | CPB2 (0.47) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL8200953 | 0.76 | CPB2 (0.51) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL19385944 | 0.76 | RNPEP (0.50) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL15641942 | 0.76 | RNPEP (0.50) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL15641943 | 0.76 | RNPEP (0.50) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL468721 | 0.76 | CPB2 (0.47) | CPB2GSRRNPEPFOLH1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785481-B2 | Ether benzotriazole derivatives | MERCK SHARP & DOHME CORP. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120135977-A1 | ETHER BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME LLC | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135977-A1 | ETHER BENZOTRIAZOLE DERIVATIVES | GRM2, GRIA2, GRIK2 | CPB2 2787/4885GSR 191/4885RNPEP 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.