SCHEMBL8512890

SCHEMBL8512890

CCCSc1ccc(N)c(N)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
MAPT P10636 4/20 0.45
AR P10275 4/20 0.44
KMT2A Q03164 5/20 0.41
MCL1 Q07820 1/20 0.39
BCL2A1 Q16548 1/20 0.39
TP53 P04637 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP3A4 P08684 2/20 0.38
ALOX15 P16050 2/20 0.38
THRB P10828 1/20 0.38
ALDH1A1 P00352 4/20 0.37
POLB P06746 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29487551 1.00 CA12 (0.47) CA12CA1CA2CA7CA13
Hydrochloric Acid SCHEMBL11812617 0.98 CA12 (0.46) CA12CA1CA2CA7CA13
SCHEMBL11660362 0.88 MAOA (0.49) CA12CA1CA2CA7CA13
SCHEMBL10424194 0.85 THRB (0.43) MAOAMAOBMAPTARKMT2A
SCHEMBL11249663 0.82 CA12 (0.47) CA12CA1CA2CA7CA13
SCHEMBL11835307 0.82 MCL1 (0.38) CA12CA1CA2CA7CA13
SCHEMBL11630502 0.81 MEN1 (0.39) CA12CA1CA2CA7CA13
SCHEMBL11752648 0.80 MCL1 (0.37) MAPTARKMT2AMCL1BCL2A1
SCHEMBL10339714 0.80 AR (0.60) CA12CA1CA2CA7CA13
SCHEMBL11272357 0.80 SLC2A1 (0.49) MAOAMAPTKMT2AMCL1BCL2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462453-A Synthesis method and application of propylthio-o-phenylenediamine 河北美荷药业有限公司 2025-02-18 CN claimed
CN-115850133-B Synthesis method of 4-propylthio-o-phenylenediamine 山东国邦药业有限公司 2023-06-06 CN claimed
CN-115850133-A Synthesis method of 4-propylthio-o-phenylenediamine 山东国邦药业有限公司 2023-03-28 CN claimed
CN-111574460-B Preparation method of albendazole 山东国邦药业有限公司 2021-11-05 CN claimed
CN-108892643-B Novel preparation method of albendazole 常州齐晖药业有限公司 2021-01-08 CN claimed
CN-112125853-A Production process and production device of albendazole 宁夏大漠药业有限公司 2020-12-25 CN claimed
CN-111574460-A Preparation method of albendazole 山东国邦药业有限公司 2020-08-25 CN claimed
US-20130303782-A1 PROCESS FOR PREPARATION OF ALBENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2013-11-14 US claimed
EP-2643304-A2 A PROCESS FOR PREPARATION OF ALBENDAZOLE Sequent Scientific Ltd. (IN) 2013-10-02 EP claimed
WO-2012070069-A2 A PROCESS FOR PREPARATION OF ALBENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2012-05-31 WO claimed
CN-119462453-A Synthesis method and application of propylthio-o-phenylenediamine 河北美荷药业有限公司 2025-02-18 CN disclosed
CN-119462453-A Synthesis method and application of propylthio-o-phenylenediamine 河北美荷药业有限公司 2025-02-18 CN disclosed
CN-119462453-A Synthesis method and application of propylthio-o-phenylenediamine 河北美荷药业有限公司 2025-02-18 CN disclosed
CN-117624055-A Preparation method of albendazole for livestock 河北美荷药业有限公司 2024-03-01 CN disclosed
CN-219922937-U Albendazole production is with alkylation reaction system 河北美荷药业有限公司 2023-10-31 CN disclosed
EP-0034421-A2 N-phenyl-N'-cyano-0-phenylisoureas and process for their preparation SMITHKLINE BECKMAN CORPORATION (US) 1981-08-26 EP disclosed
US-4285878-A N-Phenyl-N'-cyano-O-phenylisoureas SMITHKLINE CORPORATION (US) 1981-08-25 US disclosed
EP-0003951-A1 Process for the preparation of 2-benzimidazolecarbamic acid esters ETHYL CORPORATION (US) 1979-09-19 EP disclosed
US-4152522-A FROM ORTHO-NITROANILINE ETHYL CORPORATION (US) 1979-05-01 US disclosed
US-3956499-A ANTHELMINTICS SMITHKLINE CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303782-A1 PROCESS FOR PREPARATION OF ALBENDAZOLE CPS1, PNPO, NAT1 CA12 989/4885CA1 1023/4885CA2 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.