Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28130520 | 0.79 | CPB2 (0.41) | GSRCPB2RNPEPGABRR1 | |
| SCHEMBL7271506 | 0.78 | GSR (0.50) | GSRCPB2RNPEPGABRR1GLO1 | |
| SCHEMBL5280980 | 0.78 | GSR (0.50) | GSRCPB2RNPEPGABRR1GLO1 | |
| SCHEMBL28011992 | 0.77 | GSR (0.45) | GSRCPB2RNPEPGABRR1GLO1 | |
| SCHEMBL482963 | 0.74 | CPB2 (0.44) | GSRCPB2RNPEPGABRR1GLO1 | |
| SCHEMBL482961 | 0.74 | CPB2 (0.44) | GSRCPB2RNPEPGABRR1GLO1 | |
| SCHEMBL28131142 | 0.74 | GSR (0.47) | GSRCPB2RNPEPGABRR1 | |
| SCHEMBL28131140 | 0.72 | GSR (0.46) | GSRCPB2RNPEPGABRR1 | |
| SCHEMBL28130420 | 0.72 | GSR (0.46) | GSRCPB2RNPEPGABRR1 | |
| SCHEMBL28131214 | 0.72 | GSR (0.46) | GSRCPB2RNPEPGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10908169-B2 | Reagents and methods for detecting protein crotonylation | PTM BIO LLC (US) | 2021-02-02 | — | — | US | disclosed |
| US-20190137512-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN CROTONYLATION | PTM BIO LLC (US) | 2019-05-09 | — | — | US | disclosed |
| US-9625467-B2 | Agent and method for identifying lysine crotonylation in proteins | PTM BIO LLC (US) | 2017-04-18 | — | — | US | disclosed |
| CN-103183725-B | Method for detecting protein lysine crotonyl acylation modification and developing affinity reagent | 杭州景杰生物科技有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-20150065385-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN CROTONYLATION | PTM BIOLABS, INC. (US) | 2015-03-05 | — | — | US | disclosed |
| US-20130224880-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN CROTONYLATION | PTM BIOLABS, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2610266-A1 | Reagents and methods for detecting protein crotonylation | PTM Biolabs, Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| CN-103183725-A | A method of detecting protein lysine crotonylation acylation modification and developing affinity reagents | PTM BIOLABS INC | 2013-07-03 | — | — | CN | disclosed |
| US-20120135538-A1 | AGENT AND METHOD FOR IDENTIFYING LYSINE CROTONYLATION IN PROTEINS | PTM BIO LLC | 2012-05-31 | — | — | US | disclosed |