SCHEMBL8513338

SCHEMBL8513338

c1ccc(CN=NNCc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
SIGMAR1 Q99720 3/20 0.44
GRIN2D O15399 2/20 0.44
GRIN3B O60391 2/20 0.44
GRIN1 Q05586 2/20 0.44
GRIN2A Q12879 2/20 0.44
GRIN2B Q13224 2/20 0.44
GRIN2C Q14957 2/20 0.44
GRIN3A Q8TCU5 2/20 0.44
MAOA P21397 1/20 0.43
IDO1 P14902 2/20 0.43
THRB P10828 1/20 0.43
MAPT P10636 3/20 0.42
CHRM2 P08172 1/20 0.42
GAA P10253 1/20 0.42
CYP3A4 P08684 3/20 0.41
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7898992 0.89 MEN1 (0.50) MEN1KMT2ATDP1SIGMAR1MAOA
SCHEMBL7911586 0.85 MAOA (0.47) MEN1KMT2ATDP1SIGMAR1MAOA
SCHEMBL1616038 0.77 GRIN2D (0.47) MEN1KMT2ATDP1SIGMAR1GRIN2D
SCHEMBL15579853 0.76 CYP3A4 (0.43) MEN1KMT2ASIGMAR1GRIN2DGRIN3B
SCHEMBL3277759 0.76 MEN1 (0.50) MEN1KMT2ATDP1SIGMAR1MAOA
SCHEMBL3277762 0.76 MEN1 (0.50) MEN1KMT2ATDP1SIGMAR1MAOA
SCHEMBL17178869 0.75 ALDH1A1 (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19611522 0.75 ALDH1A1 (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15506263 0.75 ALDH1A1 (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2777926 0.74 TDP1 (0.48) MEN1KMT2ATDP1SIGMAR1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076940-B1 A SEALING DEVICE WITH HIGH SURFACE ROUGHNESS SIKA TECH AG (CH) 2025-06-04 EP claimed
CN-122034463-A Waterproof film with solid filler component SIKA技术股份公司 2026-05-15 CN disclosed
EP-3351526-B1 DIISOPENTYLTEREPHTHALATE EVONIK OPERATIONS GMBH (DE) 2020-11-18 EP disclosed
EP-3351526-A1 DIISOPENTYLTEREPHTHALATE Evonik Degussa GmbH (DE) 2018-07-25 EP disclosed
EP-2643157-A1 DINT IN EXPANDED PVC PASTES Evonik Oxeno GmbH (DE) 2013-10-02 EP disclosed
WO-2012069283-A1 DINT IN EXPANDED PVC PASTES EVONIK OXENO GMBH (DE) 2012-05-31 WO disclosed