Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783875 | 0.81 | — | — | |
| Iodide SCHEMBL180207 | 0.79 | CA1 (0.41) | HDAC8CA1CA2POLBAPOBEC3A | |
| SCHEMBL319283 | 0.77 | CA1 (0.42) | HDAC8CA1CA2POLBAPOBEC3A | |
| Water SCHEMBL15365843 | 0.75 | CA1 (0.41) | HDAC8CA1CA2POLBAPOBEC3A | |
| Hydrochloric Acid SCHEMBL1884665 | 0.75 | CA1 (0.41) | HDAC8CA1CA2POLBAPOBEC3A | |
| Bromide SCHEMBL8204078 | 0.75 | CA1 (0.45) | HDAC8CA1CA2POLBAPOBEC3A | |
| SCHEMBL30779767 | 0.75 | CA1 (0.45) | HDAC8CA1CA2POLBAPOBEC3A | |
| Fluoride Ion SCHEMBL21980196 | 0.75 | CA1 (0.41) | HDAC8CA1CA2POLBAPOBEC3A | |
| Iodide SCHEMBL5579282 | 0.74 | CA1 (0.38) | HDAC8CA1CA2 | |
| SCHEMBL427789 | 0.73 | CA1 (0.33) | HDAC8CA1CA2POLBAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932316-B2 | Imidazolium salts having liquid crystal characteristics, useful as electrolytes | DAUNIA SOLAR CELL S.R.L. (IT) | 2018-04-03 | — | — | US | disclosed |
| EP-2440532-B1 | Imidazolium salts having liquid crystal characteristics, useful as electrolytes | DAUNIA SOLAR CELL S R L (IT) | 2015-08-05 | — | — | EP | disclosed |
| US-20120135316-A1 | NEW IMIDAZOLIUM SALTS HAVING LIQUID CRYSTAL CHARACTERISTICS, USEFUL AS ELECTROLYTES | DAUNIA SOLAR CELL S.R.L. (IT) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135316-A1 | NEW IMIDAZOLIUM SALTS HAVING LIQUID CRYSTAL CHARACTERISTICS, USEFUL AS ELECTROLYTES | KCNH2, KCNH3, HCN2 | HDAC8 4224/4885CA1 193/4885CA2 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.