Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | EEF2K | O00418 | 2/20 | 0.35 |
| ▸ | EEF2 | P13639 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319283 | 0.98 | CA1 (0.42) | CA1CA2EEF2KEEF2KMT2A | |
| Bromide SCHEMBL8204078 | 0.96 | CA1 (0.45) | CA1CA2EEF2KEEF2KMT2A | |
| Fluoride Ion SCHEMBL21980196 | 0.96 | CA1 (0.41) | CA1CA2EEF2KEEF2KMT2A | |
| Iodide SCHEMBL180207 | 0.96 | CA1 (0.41) | CA1CA2EEF2KEEF2KMT2A | |
| SCHEMBL30779767 | 0.96 | CA1 (0.45) | CA1CA2EEF2KEEF2KMT2A | |
| Water SCHEMBL15365843 | 0.96 | CA1 (0.41) | CA1CA2EEF2KEEF2KMT2A | |
| SCHEMBL15732264 | 0.90 | CA1 (0.38) | CA1CA2EEF2KEEF2KMT2A | |
| Iodide SCHEMBL5579282 | 0.90 | CA1 (0.38) | CA1CA2EEF2KEEF2KMT2A | |
| SCHEMBL28698378 | 0.90 | CA1 (0.38) | CA1CA2EEF2KEEF2KMT2A | |
| SCHEMBL61368 | 0.90 | CA1 (0.38) | CA1CA2EEF2KEEF2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240183817-A1 | Solid-state Reference Electrode Based on Polymeric Membrane | GLAS TRUST COMPANY LLC | 2024-06-06 | — | — | US | claimed |
| EP-4341678-A1 | SOLID-STATE REFERENCE ELECTRODE BASED ON POLYMERIC MEMBRANE | Nova Biomedical Corporation (US) | 2024-03-27 | — | — | EP | claimed |
| WO-2022245347-A1 | SOLID-STATE REFERENCE ELECTRODE BASED ON POLYMERIC MEMBRANE | NOVA BIOMEDICAL CORPORATION (US) | 2022-11-24 | — | — | WO | claimed |
| CN-111224163-B | Electrolyte composition and metal ion battery comprising same | 财团法人工业技术研究院 | 2022-02-22 | — | — | CN | claimed |
| US-11258100-B2 | Electrolyte composition and metal-ion battery employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INTITUTE (TW) | 2022-02-22 | — | — | US | claimed |
| CN-111224163-A | Electrolyte composition and metal ion battery comprising same | 财团法人工业技术研究院 | 2020-06-02 | — | — | CN | claimed |
| US-20200168954-A1 | ELECTROLYTE COMPOSITION AND METAL-ION BATTERY EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2020-05-28 | — | — | US | claimed |
| CN-108767303-A | A kind of semi-solid flow cell | 山东科技大学 | 2018-11-06 | — | — | CN | claimed |
| CN-108321394-A | A kind of Dual-ion cell and preparation method thereof | 山东科技大学 | 2018-07-24 | — | — | CN | claimed |
| CN-104136445-B | Synthesis of organohalosilane monomers by enhanced cracking of direct Process residue | 莫门蒂夫性能材料股份有限公司 | 2017-11-03 | — | — | CN | claimed |
| EP-2797935-A1 | SYNTHESIS OF ORGANOHALOSILANE MONOMERS VIA ENHANCED CLEAVAGE OF DIRECT PROCESS RESIDUE | Momentive Performance Materials Inc. (US) | 2014-11-05 | — | — | EP | claimed |
| US-8715853-B1 | Aluminum batteries comprising metal-oxide, metal-fluoride, metal-sulfide, or sulfur cathodes | HRL LABORATORIES, LLC (US) | 2014-05-06 | — | — | US | claimed |
| US-8697901-B2 | Synthesis of organohalosilane monomers via enhanced cleavage of direct process residue | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-04-15 | — | — | US | claimed |
| US-8637695-B2 | Synthesis of organohalosilane monomers from conventionally uncleavable Direct Process Residue | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-01-28 | — | — | US | claimed |
| US-20130172593-A1 | Synthesis of Organohalosilane Monomers From Conventionally Uncleavable Direct Process Residue | MOMENTIVE PERFORMANCE MATERIALS INC. | 2013-07-04 | — | — | US | claimed |
| WO-2013101619-A1 | SYNTHESIS OF ORGANOHALOSILANE MONOMERS FROM CONVENTIONALLY UNCLEAVABLE DIRECT PROCESS RESIDUE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-07-04 | — | — | WO | claimed |
| US-20130172594-A1 | Synthesis of Organohalosilane Monomers Via Enhanced Cleavage of Direct Process Residue | MOMENTIVE PERFORMANCE MATERIALS INC. | 2013-07-04 | — | — | US | claimed |
| WO-2013101618-A1 | SYNTHESIS OF ORGANOHALOSILANE MONOMERS VIA ENHANCED CLEAVAGE OF DIRECT PROCESS RESIDUE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-07-04 | — | — | WO | claimed |
| US-8083945-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-12-27 | — | — | US | claimed |
| US-20100223208-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS, INC. (US) | 2010-09-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11258100-B2 | Electrolyte composition and metal-ion battery employing the same | SLC26A3, F8, CLIC1 | CA1 62/4885CA2 18/4885EEF2K 4002/4885 |
| US-20200168954-A1 | ELECTROLYTE COMPOSITION AND METAL-ION BATTERY EMPLOYING THE SAME | SLC26A3, F8, CLIC1 | CA1 62/4885CA2 18/4885EEF2K 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.