Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425143 | 0.86 | HIF1A (0.39) | ALDH1A1ADH1BADH1CADH1ATSHR | |
| SCHEMBL17866187 | 0.75 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL8767099 | 0.75 | TSHR (0.32) | ADH1BADH1CADH1ATSHRHIF1A | |
| SCHEMBL144355 | 0.74 | ADH1B (0.31) | ADH1BADH1CADH1A | |
| SCHEMBL6338673 | 0.70 | — | — | |
| SCHEMBL7595755 | 0.69 | ALDH1A1 (0.50) | ALDH1A1ADH1BADH1ATSHRHIF1A | |
| SCHEMBL6454396 | 0.69 | ALDH1A1 (0.36) | ALDH1A1ADH1BADH1CADH1ATSHR | |
| SCHEMBL3819026 | 0.67 | TSHR (0.33) | TSHR | |
| SCHEMBL15141 | 0.67 | TSHR (0.33) | TSHR | |
| SCHEMBL30272418 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643366-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORP (US) | 2015-03-25 | — | — | EP | disclosed |
| US-8895465-B2 | Activator compositions, their preparation, and their use in catalysis | ALBEMARLE CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |
| EP-2643366-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | Albemarle Corporation (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20130253155-A1 | Activator Compositions, Their Preparation, and Their Use In Catalysis | ALBEMARIE CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012071205-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORPORATION (US) | 2012-05-31 | — | — | WO | disclosed |