Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856984 | 0.87 | FNTA (0.47) | TRPV1CPA1FNTAFNTBSLC7A5 | |
| SCHEMBL5341495 | 0.78 | SLC7A5 (0.50) | CPA1FNTAFNTBSLC7A5 | |
| SCHEMBL31480546 | 0.78 | SLC7A5 (0.50) | CPA1FNTAFNTBSLC7A5 | |
| SCHEMBL432795 | 0.78 | SLC7A5 (0.49) | CPA1FNTAFNTBSLC7A5 | |
| SCHEMBL432794 | 0.78 | SLC7A5 (0.49) | CPA1FNTAFNTBSLC7A5 | |
| SCHEMBL31480614 | 0.76 | SLC7A5 (0.47) | CPA1FNTAFNTBSLC7A5 | |
| SCHEMBL5966737 | 0.75 | SLC7A5 (0.46) | CPA1FNTAFNTBSLC7A5 | |
| SCHEMBL598437 | 0.74 | CPA1 (0.54) | ADAMTS5CPA1SLC7A5 | |
| SCHEMBL598436 | 0.74 | CPA1 (0.54) | ADAMTS5CPA1SLC7A5 | |
| SCHEMBL20522201 | 0.73 | KDM6B (0.47) | CPA1KDM4ESLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136416-A1 | Caged Neuropeptides: modulation and measurement of synapse and signaling activity; and methods for drug evaluation, pharmaceuticals preparation and treatment | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-31 | — | — | US | disclosed |