Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91277 | 0.93 | TAAR1 (0.64) | LTA4HTAAR1MAOBCALM1AOC3 | |
| Ammonia Solution, Strong SCHEMBL10466463 | 0.91 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3IDO1 | |
| SCHEMBL25548721 | 0.91 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3IDO1 | |
| Hydrochloric Acid SCHEMBL7977201 | 0.91 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3IDO1 | |
| Ethylamine SCHEMBL9152431 | 0.87 | TAAR1 (0.69) | TAAR1MAOBCALM1AOC3IDO1 | |
| SCHEMBL10570923 | 0.87 | CALM1 (0.62) | TAAR1MAOBCALM1AOC3IDO1 | |
| SCHEMBL7457421 | 0.87 | MAOB (0.68) | TAAR1MAOBCALM1AOC3IDO1 | |
| SCHEMBL12736292 | 0.87 | MAOB (0.68) | TAAR1MAOBCALM1AOC3IDO1 | |
| SCHEMBL27884 | 0.86 | LTA4H (0.81) | LTA4HTAAR1IDO1SAE1UBA2 | |
| SCHEMBL25986524 | 0.86 | LTA4H (0.81) | LTA4HTAAR1IDO1SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |