Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513685 | 0.85 | — | — | |
| SCHEMBL1229647 | 0.78 | TSHR (0.34) | TSHRALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL1228257 | 0.78 | TSHR (0.34) | TSHRALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL17732447 | 0.77 | TSHR (0.46) | TSHRALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL8680820 | 0.77 | TSHR (0.46) | TSHRALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL1229908 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1LMNA | |
| SCHEMBL1230087 | 0.72 | — | — | |
| SCHEMBL1608976 | 0.72 | — | — | |
| SCHEMBL10075642 | 0.72 | TSHR (0.44) | TSHRALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL6064125 | 0.72 | TSHR (0.41) | TSHRALDH1A1LMNAUSP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136082-A1 | BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS | WACKER CHEMIE AG (DE) | 2012-05-31 | — | — | US | disclosed |