Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47840 | 0.76 | CYP3A4 (0.46) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL8377055 | 0.75 | CA1 (0.48) | CYP3A4MAOATSHRCYP1A2CYP2D6 | |
| SCHEMBL47841 | 0.74 | MCL1 (0.46) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL12440155 | 0.74 | CYP3A4 (0.48) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL3765966 | 0.72 | CYP3A4 (0.46) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL12401537 | 0.72 | CYP3A4 (0.46) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL8516125 | 0.70 | TACR1 (0.52) | — | |
| SCHEMBL7060861 | 0.70 | TSHR (0.40) | CYP3A4TSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5484161 | 0.68 | CYP3A4 (0.42) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL77470 | 0.68 | CYP3A4 (0.48) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859762-B2 | Methods for ultrasonication-assisted chlorination of aromatic compounds | PEKING UNIVERSITY (CN) | 2014-10-14 | — | — | US | claimed |
| US-20120277422-A1 | METHODS FOR ULTRASONICATION-ASSISTED CHLORINATION OF AROMATIC COMPOUNDS | PEKING UNIVERSITY | 2012-11-01 | — | — | US | claimed |
| WO-2012068740-A1 | METHODS FOR ULTRASONICATION-ASSISTED CHLORINATION OF AROMATIC COMPOUNDS | PEKING UNIVERSITY (CN) | 2012-05-31 | — | — | WO | claimed |
| US-8859762-B2 | Methods for ultrasonication-assisted chlorination of aromatic compounds | PEKING UNIVERSITY (CN) | 2014-10-14 | — | — | US | disclosed |
| US-20120277422-A1 | METHODS FOR ULTRASONICATION-ASSISTED CHLORINATION OF AROMATIC COMPOUNDS | PEKING UNIVERSITY | 2012-11-01 | — | — | US | disclosed |
| WO-2012068740-A1 | METHODS FOR ULTRASONICATION-ASSISTED CHLORINATION OF AROMATIC COMPOUNDS | PEKING UNIVERSITY (CN) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277422-A1 | METHODS FOR ULTRASONICATION-ASSISTED CHLORINATION OF AROMATIC COMPOUNDS | RNF168, AHR, ERCC2 | CYP3A4 524/4885CHRM1 2238/4885ALOX15 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.