Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451462 | 0.81 | HTR2A (0.40) | HTR2BS1PR2S1PR4S1PR1S1PR5 | |
| SCHEMBL91292 | 0.78 | LOXL2 (0.35) | PNMTS1PR2S1PR4S1PR1S1PR5 | |
| SCHEMBL2003716 | 0.77 | CD44 (0.38) | CYP3A4PNMTS1PR2S1PR4S1PR1 | |
| SCHEMBL20020024 | 0.77 | MAOA (0.39) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL12440155 | 0.76 | CYP3A4 (0.48) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL4351698 | 0.76 | ALDH1A1 (0.52) | CYP3A4LOXL2ALDH1A1TAAR1NSD3 | |
| SCHEMBL15874052 | 0.76 | HTR1D (0.38) | PNMTLOXL2ENPP2NSD3 | |
| SCHEMBL23328350 | 0.75 | CSNK2A1 (0.37) | HTR2BPNMTS1PR2S1PR4S1PR1 | |
| SCHEMBL14145128 | 0.75 | SIRT1 (0.39) | CYP3A4ALOX15S1PR2S1PR4S1PR1 | |
| SCHEMBL15787530 | 0.75 | MAOA (0.43) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190258-A1 | ARYL BENZYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190258-A1 | ARYL BENZYLAMINE COMPOUNDS | UGT2B7, NAT1, CYP2B6 | CYP3A4 12/4885CHRM1 1170/4885ALOX15 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.